Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | FADS1 | O60427 | 2/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | FERMT2 | Q96AC1 | 2/20 | 0.36 |
| ▸ | FLT1 | P17948 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237340 | 1.00 | LOXL2 (0.44) | LOXL2CYP1A2FADS1TGFBR1NCF1 | |
| SCHEMBL5234977 | 0.84 | LOXL2 (0.49) | LOXL2CYP1A2NCF1FERMT2CYP3A4 | |
| SCHEMBL5237043 | 0.84 | LOXL2 (0.49) | LOXL2CYP1A2NCF1FERMT2CYP3A4 | |
| SCHEMBL5241402 | 0.84 | FADS1 (0.46) | LOXL2CYP1A2FADS1TGFBR1FLT1 | |
| SCHEMBL5241399 | 0.84 | FADS1 (0.46) | LOXL2CYP1A2FADS1TGFBR1FLT1 | |
| SCHEMBL5237978 | 0.82 | CYP1A2 (0.42) | LOXL2CYP1A2NCF1FERMT2KDR | |
| SCHEMBL5241334 | 0.82 | CYP1A2 (0.42) | LOXL2CYP1A2NCF1FERMT2KDR | |
| SCHEMBL5238458 | 0.82 | LOXL2 (0.46) | LOXL2CYP1A2FADS1NCF1FERMT2 | |
| SCHEMBL5238455 | 0.82 | LOXL2 (0.46) | LOXL2CYP1A2FADS1NCF1FERMT2 | |
| SCHEMBL5236327 | 0.81 | LOXL2 (0.43) | LOXL2CYP1A2FADS1TGFBR1NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397364-B1 | NOVEL PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | LILLY CO ELI (US) | 2007-07-25 | — | — | EP | disclosed |