Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PTPRG | P23470 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5130053 | 0.86 | PNMT (0.58) | PNMTTSHRTACR1SMN1; SMN2SIGMAR1 | |
| SCHEMBL6003855 | 0.86 | PNMT (0.58) | PNMTTSHRTACR1SMN1; SMN2SIGMAR1 | |
| SCHEMBL6005581 | 0.86 | PNMT (0.58) | PNMTTSHRTACR1SMN1; SMN2SIGMAR1 | |
| SCHEMBL5972040 | 0.83 | PNMT (0.54) | PNMTTSHRTACR1SMN1; SMN2HRH3 | |
| SCHEMBL15745969 | 0.82 | PNMT (0.62) | PNMTTSHRTACR1SMN1; SMN2IDO1 | |
| SCHEMBL683674 | 0.82 | PNMT (0.62) | PNMTTSHRTACR1SMN1; SMN2IDO1 | |
| SCHEMBL21930623 | 0.82 | PNMT (0.62) | PNMTTSHRTACR1SMN1; SMN2IDO1 | |
| SCHEMBL1036143 | 0.82 | PNMT (0.53) | PNMTTSHRTACR1SMN1; SMN2HRH3 | |
| SCHEMBL8221816 | 0.81 | TSHR (0.55) | PNMTTSHRTACR1SMN1; SMN2HRH3 | |
| SCHEMBL6573908 | 0.81 | TSHR (0.55) | PNMTTSHRTACR1SMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392421-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023028238-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2023-03-02 | — | — | WO | disclosed |
| EP-1851232-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | Prosidion Limited (GB) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006085118-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | PROSIDION LIMITED (GB) | 2006-08-17 | — | — | WO | disclosed |