SCHEMBL5235295

SCHEMBL5235295

CCCC1C=CC=CC1(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
SHBG P04278 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809093 0.74 ESR1 (0.35) ESR1ESR2
SCHEMBL4620415 0.67
SCHEMBL6546850 0.66
SCHEMBL6453699 0.62 ESR1 (0.45) ESR1ESR2SHBG
SCHEMBL28215364 0.62 ESR2 (0.34) ESR1ESR2
SCHEMBL10903926 0.60 ESR2 (0.37) ESR1ESR2SHBG
SCHEMBL8021816 0.60 ESR2 (0.50) ESR1ESR2SHBG
Hydroquinone SCHEMBL8441656 0.60 LMNA (0.61) ESR1ESR2SHBG
SCHEMBL8583721 0.59 ESR2 (0.32) ESR1ESR2
SCHEMBL16245214 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1805130-A1 METHOD FOR THE PREPARATION OF ALIPHATIC CHLOROFORMATES General Electric Company, (a New York Corporation) (US) 2007-07-11 EP disclosed
WO-2006044575-A1 METHOD FOR THE PREPARATION OF ALIPHATIC CHLOROFORMATES GENERAL ELECTRIC COMPANY (US) 2006-04-27 WO disclosed
EP-0557950-B1 Polyetherketones and polyethersulphones based on phenylindane and their use for optical systems HOECHST AG (DE) 1996-10-30 EP disclosed
US-5373081-A Radiation transparent HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-13 US disclosed
EP-0557950-A2 Polyetherketones and polyethersulphones based on phenylindane and their use for optical systems HOECHST AKTIENGESELLSCHAFT (DE) 1993-09-01 EP disclosed
EP-0471703-A1 POLYARLYLETHER KETONES CONTAINING INDANE AND USE OF AMORPHOUS POLYARLYETHER KETONES IN OPTICAL SYSTEMS HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-26 EP disclosed
WO-1990014378-A1 POLYARLYLETHER KETONES CONTAINING INDANE AND USE OF AMORPHOUS POLYARLYETHER KETONES IN OPTICAL SYSTEMS HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-29 WO disclosed