Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5241268 | 0.82 | MALT1 (0.48) | DRD2DRD3SLC6A4MALT1 | |
| SCHEMBL5240235 | 0.80 | GRIN2B (0.56) | DRD2DRD3FYNGRIN2B | |
| SCHEMBL5240247 | 0.80 | GRIN2B (0.56) | DRD2DRD3FYNGRIN2B | |
| SCHEMBL5243488 | 0.80 | MALT1 (0.47) | DRD2DRD3SLC6A4MALT1 | |
| SCHEMBL5240970 | 0.76 | OPRM1 (0.49) | FYNKDM1AMAOAMAOBGRIN2B | |
| SCHEMBL7246202 | 0.76 | SLC6A4 (0.46) | DRD2DRD3ABCB1FYNKDM1A | |
| SCHEMBL7246206 | 0.76 | SLC6A4 (0.46) | DRD2DRD3ABCB1FYNKDM1A | |
| SCHEMBL14692494 | 0.74 | DRD2 (0.42) | DRD2DRD3ABCB1KDM1ASLC6A4 | |
| SCHEMBL22644953 | 0.73 | FYN (0.49) | DRD2DRD3FYNKDM1AGRIN2B | |
| SCHEMBL5860952 | 0.72 | MALT1 (0.49) | DRD2DRD3MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819690-A2 | CHROMAN COMPOUNDS | Pfizer Limited (GB) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056850-A2 | CHROMAN COMPOUNDS | PFIZER LIMITED (GB) | 2006-06-01 | — | — | WO | disclosed |