Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | DRD3 | P35462 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5862840 | 0.80 | MALT1 (0.47) | MALT1MTNR1ALMNAPOLBMAPT | |
| SCHEMBL5241268 | 0.79 | MALT1 (0.48) | MALT1MTNR1ADRD2DRD3 | |
| SCHEMBL5243488 | 0.77 | MALT1 (0.47) | MALT1MTNR1ADRD2DRD3 | |
| SCHEMBL21810870 | 0.74 | MALT1 (0.54) | MALT1MTNR1ADRD2DRD3LMNA | |
| SCHEMBL21810873 | 0.74 | MALT1 (0.54) | MALT1MTNR1ADRD2DRD3LMNA | |
| SCHEMBL5236147 | 0.72 | DRD2 (0.47) | MALT1DRD2DRD3 | |
| SCHEMBL21810791 | 0.72 | MALT1 (0.41) | MALT1DRD2DRD3 | |
| SCHEMBL21810787 | 0.72 | MALT1 (0.41) | MALT1DRD2DRD3 | |
| SCHEMBL31069257 | 0.72 | MALT1 (0.41) | MALT1DRD2DRD3 | |
| SCHEMBL1519378 | 0.70 | MALT1 (0.45) | MALT1DRD2DRD3HCRTR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053223-B2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-05-30 | — | — | US | disclosed |
| US-20040181068-A1 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181068-A1 | Inhibitors of farnesyl protein transferase | FNTA, FNTB, ACAT2 | MALT1 2972/4885MTNR1A 3879/4885DRD2 4884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.