Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5622818 | 0.93 | ALDH1A1 (0.39) | ALDH1A1KMT2APOLBTSHREGLN2 | |
| SCHEMBL5433058 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KMT2AENPP1POLBTSHR | |
| SCHEMBL4819849 | 0.86 | MBOAT4 (0.44) | ALDH1A1KMT2AENPP1POLBTSHR | |
| SCHEMBL4810439 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KMT2AENPP1POLBTSHR | |
| SCHEMBL4820443 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KMT2AENPP1POLBTSHR | |
| SCHEMBL4818702 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KMT2AENPP1POLBTSHR | |
| SCHEMBL7956372 | 0.83 | LMNA (0.40) | ALDH1A1KMT2AENPP1POLBTSHR | |
| SCHEMBL7958877 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KMT2AENPP1POLBTSHR | |
| SCHEMBL6998549 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KMT2AENPP1POLBTSHR | |
| SCHEMBL6998016 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KMT2AENPP1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782997-B1 | Triazolopyrimidine derivatives | SHELL INT RESEARCH (NL) | 2000-04-26 | — | — | EP | claimed |
| EP-0782997-A2 | Triazolopyrimidine derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1997-07-09 | — | — | EP | claimed |
| EP-1751162-A1 | TRIAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005113555-A1 | TRIAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-01 | — | — | WO | disclosed |
| EP-1359150-A2 | A process and intermediates for the preparation of fungicidal 7-alkyl-triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2003-11-05 | — | — | EP | disclosed |
| EP-0770615-B1 | Process for the preparation of dihaloazolopyrimidines | BASF AG (DE) | 2003-06-18 | — | — | EP | disclosed |
| EP-0782997-B1 | Triazolopyrimidine derivatives | SHELL INT RESEARCH (NL) | 2000-04-26 | — | — | EP | disclosed |
| US-5808066-A | CYCLIZATION REACTION OF 5-AMINO-(1H)-1,2,4-TRIAZOLE WITH MALONIC ACID DIESTER; SALT FORMATION, ACIDIFICATION, HALOGENATION | AMERICAN CYANAMID COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0770615-A1 | Process for the preparation of dihaloazolopyrimidines | American Cyanamid Company (US) | 1997-05-02 | — | — | EP | disclosed |
| US-5593996-A | FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1997-01-14 | — | — | US | disclosed |