Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.47 |
| ▸ | HTR3B | O95264 | 3/20 | 0.47 |
| ▸ | HTR3A | P46098 | 3/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.43 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272847 | 0.93 | ADRB1 (0.53) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5232683 | 0.91 | CHRNB2 (0.46) | CHRNB2CHRNA4ADRB1HTR3EHTR3B | |
| SCHEMBL4809382 | 0.84 | CHKA (0.51) | CHKAUSP2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL12676672 | 0.83 | CHKA (0.53) | CHKAUSP2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL5238064 | 0.82 | HTR7 (0.51) | CHRNB2CHRNA4ADRB1HTR3EHTR3B | |
| SCHEMBL5237023 | 0.80 | CHRNB2 (0.54) | CHRNB2CHRNA4ADRB1HTR3EHTR3B | |
| SCHEMBL5232578 | 0.80 | CETP (0.48) | CHRNB2CHRNA4ADRB1HTR3EHTR3B | |
| SCHEMBL12298703 | 0.80 | ADRB1 (0.50) | CHRNB2CHRNA4ADRB1HTR3EHTR3B | |
| SCHEMBL5237317 | 0.80 | ADRB1 (0.55) | CHRNB2CHRNA4ADRB1HTR3EHTR3B | |
| SCHEMBL3318505 | 0.79 | ADRB1 (0.57) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |