Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.59 |
| ▸ | GBA1 | P04062 | 2/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | CKS1B | P61024 | 1/20 | 0.53 |
| ▸ | SKP1 | P63208 | 1/20 | 0.53 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 5/20 | 0.50 |
| ▸ | AKT2 | P31751 | 5/20 | 0.50 |
| ▸ | AKT3 | Q9Y243 | 5/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12215173 | 0.95 | KIT (0.64) | KITGBA1CKS1BSKP1SKP2 | |
| SCHEMBL30060479 | 0.85 | MTNR1B (0.50) | KITGBA1PDE10AHRH4PDGFRB | |
| SCHEMBL25656100 | 0.83 | KIT (0.53) | KITPDE10ACKS1BSKP1SKP2 | |
| SCHEMBL30406162 | 0.83 | KIT (0.52) | KITGBA1HRH4PDGFRBMAP4K4 | |
| SCHEMBL3768455 | 0.83 | PRKDC (0.57) | KITGBA1PDGFRBMAP4K4LMNA | |
| SCHEMBL2916238 | 0.82 | KIT (0.62) | KITGBA1CKS1BSKP1SKP2 | |
| SCHEMBL23726903 | 0.82 | ACHE (0.67) | KITPDGFRB | |
| SCHEMBL20223124 | 0.81 | MAP4K4 (0.58) | KITGBA1PDE10ACKS1BSKP1 | |
| SCHEMBL30945078 | 0.81 | JAK3 (0.63) | KITAKT1 | |
| SCHEMBL29230295 | 0.81 | JAK3 (0.63) | KITAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | SANKYO COMPANY, LIMITED (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | RASGRP1, NRAS, HRH3 | KIT 86/4885GBA1 4304/4885PDE10A 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.