SCHEMBL3768455

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30902159	0.85	KIT (0.57)	KITMAP4K4ALDH1A1ACHEBACE1
	SCHEMBL10058374	0.85	MAP4K4 (0.61)	KITMAP4K4MAPTALDH1A1LMNA
	SCHEMBL2570926	0.83	PRKDC (0.65)	PRKDCMAP4K4ACHEBACE1PDGFRB
	SCHEMBL5237116	0.83	KIT (0.59)	KITMAP4K4LMNACNR1CNR2
	SCHEMBL3561090	0.82	GPR119 (0.47)	—
	SCHEMBL12215173	0.82	KIT (0.64)	KITMAP4K4LMNACNR1CNR2
	SCHEMBL25656100	0.82	KIT (0.53)	KITMAP4K4ACHEBACE1MEN1
	SCHEMBL2916238	0.81	KIT (0.62)	KITMAP4K4ACHEBACE1CNR1
	SCHEMBL3564744	0.81	GPR119 (0.47)	—
	SCHEMBL2918437	0.80	KIT (0.56)	KITMAP4K4ACHEBACE1PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.