Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230844 | 0.83 | GPR35 (0.39) | MAPTALDH1A1HPGD | |
| SCHEMBL5233431 | 0.80 | CA12 (0.44) | KMT2ACES2CES1ALDH1A1LMNA | |
| SCHEMBL5230393 | 0.75 | CA12 (0.42) | MAPTKMT2AKDM4EPDPK1ALDH1A1 | |
| SCHEMBL2895230 | 0.73 | PIM1 (0.45) | MAPTKMT2AKDM4EDAO | |
| SCHEMBL5233191 | 0.71 | GPR35 (0.54) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL1819697 | 0.71 | SLC16A3 (0.39) | GAAKMT2AKDM4EPDPK1ALDH1A1 | |
| SCHEMBL9069002 | 0.69 | GPR35 (0.62) | ALDH1A1LMNAHPGDTSHRHSD17B10 | |
| SCHEMBL19546521 | 0.69 | CES2 (0.41) | GAAKMT2ACES2CES1ERN1 | |
| SCHEMBL3364697 | 0.68 | GPR35 (0.45) | — | |
| SCHEMBL20559444 | 0.68 | MAPT (0.44) | MAPTGAAKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461335-B1 | 2-HETEROARYLCARBOXYLIC ACID AMIDES | BAYER HEALTHCARE AG (DE) | 2007-02-28 | — | — | EP | disclosed |