Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.45 |
| ▸ | COMT | P21964 | 4/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609267 | 0.78 | GPR35 (0.51) | GPR35COMTMCL1CDK2 | |
| SCHEMBL6490859 | 0.75 | GPR35 (0.76) | GPR35COMT | |
| SCHEMBL5237896 | 0.73 | MAOA (0.56) | GPR35 | |
| SCHEMBL3364327 | 0.70 | COMT (0.47) | COMTCDK2 | |
| SCHEMBL5235606 | 0.70 | MAPT (0.55) | MCL1PKM | |
| SCHEMBL6479672 | 0.69 | ADORA3 (0.59) | GPR35PKM | |
| SCHEMBL5237128 | 0.68 | MAPT (0.37) | — | |
| SCHEMBL5233431 | 0.66 | CA12 (0.44) | — | |
| SCHEMBL5203098 | 0.66 | MAOA (0.45) | — | |
| SCHEMBL5233703 | 0.66 | MAOB (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910325-B1 | NEW PHARMACEUTICAL COMPOUNDS | ORION CORP (FI) | 2010-10-06 | — | — | EP | claimed |