Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232330 | 0.96 | MGLL (0.64) | MGLLKDM4ESLC6A7GRIN2BGRIN1 | |
| SCHEMBL5234185 | 0.88 | KDM4E (0.59) | MGLLKDM4EPOLBSLC6A7CYP2C9 | |
| SCHEMBL3074677 | 0.83 | KDM4E (0.71) | KDM4EPOLBCYP2C9PKMHTT | |
| SCHEMBL5232948 | 0.83 | MGLL (0.60) | MGLLKDM4EPOLBSLC6A7CYP2C9 | |
| SCHEMBL5236004 | 0.82 | SMN1; SMN2 (0.52) | MGLLKDM4EPOLBSLC6A7GRIN2B | |
| SCHEMBL5237599 | 0.81 | EGLN1 (0.55) | MGLLKDM4EPKMHTTLMNA | |
| SCHEMBL31590101 | 0.79 | FYN (0.53) | MGLLSLC6A7CNR2ALDH1A1L3MBTL1 | |
| SCHEMBL5238917 | 0.79 | SMN1; SMN2 (0.56) | MGLLKDM4ESLC6A7GRIN2BGRIN1 | |
| SCHEMBL3442393 | 0.79 | MGLL (0.58) | MGLLPOLBSLC6A7HTTLMNA | |
| SCHEMBL5233253 | 0.78 | KDM4E (0.46) | MGLLKDM4EPOLBSLC6A7PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |