Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | USP2 | O75604 | 4/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | ME2 | P23368 | 1/20 | 0.50 |
| ▸ | ME1 | P48163 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631962 | 0.88 | ALDH1A1 (0.69) | MEN1KMT2ASLC6A7POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL5492248 | 0.86 | ALDH1A1 (0.67) | MEN1KMT2ASLC6A7POLBALDH1A1 | |
| SCHEMBL5233523 | 0.86 | TSHR (0.59) | MEN1KMT2ASLC6A7POLBALDH1A1 | |
| SCHEMBL5237158 | 0.86 | KMT2A (0.68) | MEN1KMT2ASLC6A7POLBALDH1A1 | |
| SCHEMBL5233832 | 0.86 | LMNA (0.62) | MEN1KMT2ASLC6A7POLBALDH1A1 | |
| SCHEMBL5238969 | 0.84 | USP2 (0.59) | MEN1KMT2ASLC6A7POLBALDH1A1 | |
| Fluoride SCHEMBL27569822 | 0.82 | MEN1 (0.56) | MEN1KMT2ASLC6A7POLBALDH1A1 | |
| SCHEMBL14438077 | 0.82 | MAPT (0.74) | MEN1KMT2ASLC6A7POLBALDH1A1 | |
| SCHEMBL5231928 | 0.82 | CA12 (0.66) | MEN1KMT2ASLC6A7POLBMAPK1 | |
| SCHEMBL5235731 | 0.82 | PANK3 (0.54) | MEN1KMT2ASLC6A7POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |