Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5240856 | 0.89 | ALOX5 (0.47) | OXER1PLA2G2AALOX5 | |
| SCHEMBL5237509 | 0.85 | ALOX5 (0.41) | KDM4EALDH1A1TSHRHSD17B10PLA2G2A | |
| SCHEMBL2085240 | 0.82 | KMT2A (0.48) | KDM4ENR4A2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5950819 | 0.82 | SRC (0.51) | KDM4ENR4A2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL5239346 | 0.77 | ALOX5 (0.48) | KDM4EALDH1A1ALOX15PLA2G2AALOX5 | |
| SCHEMBL5746650 | 0.75 | MAPK8 (0.45) | OXER1MAPK8MAPK9HIF1AMCL1 | |
| SCHEMBL4843888 | 0.73 | GAA (0.43) | OXER1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL24482981 | 0.72 | MAPK8 (0.44) | KDM4ENR4A2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4841109 | 0.72 | ALOX15 (0.50) | OXER1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5234885 | 0.70 | SMN1; SMN2 (0.52) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603914-B1 | COMPOUNDS HAVING ACTIVITY AT 5HT2C RECEPTOR AND USES THEREOF | GLAXO GROUP LTD (GB) | 2007-01-17 | — | — | EP | disclosed |