Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718244 | 1.00 | POLB (0.30) | POLBAPEX1TDP1 | |
| SCHEMBL7710249 | 0.84 | POLB (0.31) | POLBAPEX1TDP1 | |
| SCHEMBL14457412 | 0.81 | — | — | |
| SCHEMBL18885197 | 0.81 | — | — | |
| SCHEMBL10139365 | 0.81 | — | — | |
| SCHEMBL1269453 | 0.81 | — | — | |
| SCHEMBL6160829 | 0.81 | — | — | |
| SCHEMBL6159466 | 0.81 | — | — | |
| SCHEMBL5434380 | 0.81 | — | — | |
| SCHEMBL16704702 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263735-B1 | ACID ADDITION SALTS OF IMIDAZOLIDINONES AS REACTION CATALYSTS | UNIV CALIFORNIA (US) | 2007-07-04 | — | — | EP | disclosed |
| US-6534434-B2 | Catalyst for unsaturated carbonyl compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-03-18 | — | — | US | disclosed |
| US-6515137-B2 | Enantioselectivity of alpha,beta-unsaturated aldehydes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-02-04 | — | — | US | disclosed |
| US-6369243-B1 | ACID CATALYST | THE REGENTS OF THE UNIVERISITY OF CALIFORNIA | 2002-04-09 | — | — | US | disclosed |
| US-20020016473-A1 | Catalytic processes employing chiral imidazolidinone-based catalyst composition | MACMILLAN DAVID W C (US) | 2002-02-07 | — | — | US | disclosed |
| US-20020013475-A1 | Chiral imidazolidinone-based catalyst composition and reaction system | MACMILLAN DAVID W C (US) | 2002-01-31 | — | — | US | disclosed |
| US-6307057-B1 | CATALYZE ENANTIOSELECTIVE REACTIONS, E.G., DIELS-ALDER REACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013475-A1 | Chiral imidazolidinone-based catalyst composition and reaction system | COASY, DHPS, INTS9 | POLB 1301/4885APEX1 861/4885TDP1 3291/4885 |
| US-20020016473-A1 | Catalytic processes employing chiral imidazolidinone-based catalyst composition | COASY, ALDH3A1, TALDO1 | POLB 502/4885APEX1 423/4885TDP1 2459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.