SCHEMBL718244

SCHEMBL718244

O=CC1CC2C=CC1CC2

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5240932 1.00 POLB (0.30) POLBAPEX1TDP1
SCHEMBL7710249 0.84 POLB (0.31) POLBAPEX1TDP1
SCHEMBL14457412 0.81
SCHEMBL18885197 0.81
SCHEMBL10139365 0.81
SCHEMBL1269453 0.81
SCHEMBL6160829 0.81
SCHEMBL6159466 0.81
SCHEMBL5434380 0.81
SCHEMBL16704702 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559703-B2 Fragrance composition GIVAUDAN SA (CH) 2026-02-24 US claimed
EP-4655373-A1 BIODEGRADABLE PERFUME COMPOSITION Givaudan SA (CH) 2025-12-03 EP claimed
US-12234253-B2 Silicone compounds with a substituted amine group and a benefit agent moiety THE PROCTER & GAMBLE COMPANY (US) 2025-02-25 US claimed
US-20250051370-A1 SILICONE COMPOUNDS PROCTER & GAMBLE (US) 2025-02-13 US claimed
WO-2024213536-A1 FRAGRANCE COMPOSITION GIVAUDAN SA (CH) 2024-10-17 WO claimed
US-20240301331-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2024-09-12 US claimed
WO-2024156688-A1 BIODEGRADABLE PERFUME COMPOSITION GIVAUDAN SA (CH) 2024-08-02 WO claimed
EP-4407019-A1 BIODEGRADABLE PERFUME COMPOSITION Givaudan SA (CH) 2024-07-31 EP claimed
EP-4294906-A1 IMPROVEMENT IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2023-12-27 EP claimed
US-20230151305-A1 FRAGRANCE COMPOSITION SA, GIVAUDAN (CH) 2023-05-18 US claimed
US-20220064191-A1 SILICONE COMPOUNDS PROCTER & GAMBLE (US) 2022-03-03 US claimed
WO-2021224201-A1 FRAGRANCE COMPOSITION GIVAUDAN SA (CH) 2021-11-11 WO claimed
EP-3218425-B1 SILICONE COMPOUNDS PROCTER & GAMBLE (US) 2020-05-13 EP claimed
US-10336966-B2 Fragrance compositions and uses thereof THE PROCTER & GAMBLE COMPANY (US) 2019-07-02 US claimed
WO-2017196762-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2017-11-16 WO claimed
US-20170327647-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2017-11-16 US claimed
US-20170290757-A1 MALODOR REDUCING COMPOSITIONS GIVAUDAN S.A. (CH) 2017-10-12 US claimed
EP-3218425-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2017-09-20 EP claimed
WO-2016077513-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2016-05-19 WO claimed
US-20160137674-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2016-05-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160137674-A1 SILICONE COMPOUNDS SMCHD1, SRI, SMS POLB 3490/4885APEX1 4489/4885TDP1 2993/4885
US-20250051370-A1 SILICONE COMPOUNDS SMCHD1, SRI, SMS POLB 3490/4885APEX1 4489/4885TDP1 2993/4885
US-12559703-B2 Fragrance composition DHCR24, OPRD1, OR10J3 POLB 3087/4885APEX1 4398/4885TDP1 3363/4885
US-12234253-B2 Silicone compounds with a substituted amine group and a benefit agent moiety SMS, SRM, AAAS POLB 2364/4885APEX1 3532/4885TDP1 1530/4885
US-10336966-B2 Fragrance compositions and uses thereof CUTA, DPM1, PLIN5 POLB 402/4885APEX1 590/4885TDP1 1071/4885
US-20220064191-A1 SILICONE COMPOUNDS SMCHD1, SRI, SMS POLB 3490/4885APEX1 4489/4885TDP1 2993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.