Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272229 | 0.97 | — | — | |
| SCHEMBL8565462 | 0.80 | — | — | |
| SCHEMBL910633 | 0.78 | — | — | |
| Ethylene SCHEMBL28538097 | 0.78 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL1573174 | 0.77 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL1437889 | 0.77 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL4557504 | 0.77 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL19691908 | 0.76 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL1611049 | 0.76 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL1476715 | 0.76 | ALOX5 (0.55) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254907-B1 | PYRROLOPYRIDAZINE COMPOUND | SANKYO CO (JP) | 2007-05-09 | — | — | EP | disclosed |
| CN-1285593-C | Pyrrolopyridazine compound | SANKYO CO (JP) | 2006-11-22 | — | — | CN | disclosed |
| US-6734181-B2 | GASTRIC ACID SECRETORY INHIBITION ACTIVITY, GASTRIC MUCOUS MEMBRANE PROTECTION ACTIVITY; TREATMENT OF ULCERS AND HELICOBACTER PYLORI INFECIONS | SANKYO COMPANY, LIMITED (JP) | 2004-05-11 | — | — | US | disclosed |
| US-20040014762-A1 | Pyrrolopyridazine compounds | SANKYO COMPANY, LIMITED (JP) | 2004-01-22 | — | — | US | disclosed |
| CN-1422272-A | Pyrrolopyridazine compound | SANKYO CO (JP) | 2003-06-04 | — | — | CN | disclosed |
| EP-1254907-A1 | PYRROLOPYRIDAZINE COMPOUND | Sankyo Company, Limited (JP) | 2002-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014762-A1 | Pyrrolopyridazine compounds | HRH2, ADH1C, GIPR | ALOX5 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.