SCHEMBL524341

SCHEMBL524341

CC1(C)CC(CCCCNc2nc(Cl)nc(Cl)n2)CC(C)(C)N1OC1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.33
TNKS2 Q9H2K2 1/20 0.31
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL452494 0.98 KMT2A (0.36) KMT2ATNKS2SIGMAR1
SCHEMBL9429087 0.97 KMT2A (0.38) KMT2ATNKS2SIGMAR1
SCHEMBL9428448 0.97 KMT2A (0.38) KMT2ATNKS2SIGMAR1
SCHEMBL1231055 0.92 TNKS2 (0.34) TNKS2SIGMAR1
SCHEMBL8653406 0.89
SCHEMBL526852 0.87 KMT2A (0.36) KMT2ATNKS2
SCHEMBL9428266 0.87 TLR7 (0.36) TNKS2SIGMAR1
SCHEMBL9428465 0.86
SCHEMBL9428455 0.86 KMT2A (0.38) KMT2ATNKS2SIGMAR1
SCHEMBL9428473 0.86 TLR7 (0.35) KMT2ATNKS2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10414985-B2 Heptaphosphorus-derived compounds as flame retardants BASF SE (DE) 2019-09-17 US claimed
US-10385213-B2 Candle wax compositions stabilized with UV absorbers and select hindered amine light stabilizers BASF SE (DE) 2019-08-20 US claimed
US-20180216008-A1 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2018-08-02 US claimed
EP-3122813-B1 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2018-03-07 EP claimed
US-20180002527-A1 CANDLE WAX COMPOSITIONS STABILIZED WITH UV ABSORBERS AND SELECT HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2018-01-04 US claimed
EP-3122813-A2 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2017-02-01 EP claimed
WO-2015144667-A2 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2015-10-01 WO claimed
US-20150148464-A1 FLAME RETARDANT COMPOSITIONS OF PHOSPHINIC ACID SALTS AND NITROXYL DERIVATIVES BASF SE (DE) 2015-05-28 US claimed
US-20140316032-A1 P-N-COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2014-10-23 US claimed
EP-2780412-A1 P-PIPERAZINE COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2014-09-24 EP claimed
US-20030130384-A1 Flame retardant compositions HORSEY DOUGLAS WAYNE (US) 2003-07-10 US claimed
US-20030101640-A1 Candle wax compositions stabilized with UV absorber-metal combinations WOOD MERVIN (US) 2003-06-05 US claimed
US-6562085-B1 Against discoloration and fading; antioxidant; benzotriazole-metal complex or benzotriazole-metal salt compounds CIBA SPECIALTY CHEMICALS CORPORATION 2003-05-13 US claimed
EP-1252227-A1 CANDLE WAX STABILIZED BY A COMBINATION OF UV ABSORBER PLUS A SELECTED HINDERED AMINE Ciba SC Holding AG (CH) 2002-10-30 EP claimed
US-6472456-B1 POLYOLEFINS, ESPECIALLY POLYPROPYLENE, CAN BE MADE FLAME RETARDANT BY THE INCORPORATION THEREIN OF A SYNERGISTIC MIXTURE OF A SELECTED HINDERED AMINE SUBSTITUTED BY AN ALKOXY, CYDOALKOXY OR HYDROXYALKOXY MOIETY AND A SELECTED CIBA SPECIALTY CHEMICALS CORP. 2002-10-29 US claimed
US-20020010235-A1 Polymer substrate, and a synergistic mixture of a hindered amine and a phosphorus or bromine compound. HORSEY DOUGLAS WAYNE (US) 2002-01-24 US claimed
US-6296674-B1 Candle wax stabilized with red-shift benzotriazoles CIBA SPECIALTY CHEMICALS CORPORATION 2001-10-02 US claimed
WO-2001057126-A1 CANDLE WAX STABILIZED BY A COMBINATION OF UV ABSORBER PLUS A SELECTED HINDERED AMINE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-09 WO claimed
WO-2001057125-A1 CANDLE WAX STABILIZED WITH RED-SHIFTED BENZOTRIAZOLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-09 WO claimed
US-6221115-B1 WHITE, DYED, DIPPED, UNSCENTED AND/OR SCENTED CANDLE WAX STABILIZED BY A ULTRAVILET RADIATION ABSORBER AND HINDERED AMINE STABILIZING AGENT CIBA SPECIALTY CHEMICALS CORPORATION 2001-04-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180216008-A1 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS PFAS, PCBP1, DDT KMT2A 1171/4885TNKS2 1832/4885SIGMAR1 2954/4885
US-10414985-B2 Heptaphosphorus-derived compounds as flame retardants PFAS, PCBP1, DDT KMT2A 1058/4885TNKS2 1657/4885SIGMAR1 3026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.