Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243502 | 0.98 | ALOX5 (0.30) | ALOX5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5838810 | 0.78 | CYP2E1 (0.39) | SMN1; SMN2 | |
| SCHEMBL16702126 | 0.76 | ALDH1A1 (0.39) | ALOX5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5243514 | 0.71 | — | — | |
| SCHEMBL5246863 | 0.70 | ALDH1A1 (0.38) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22171244 | 0.65 | ALDH1A1 (0.51) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12853572 | 0.64 | — | — | |
| SCHEMBL5622837 | 0.63 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16701552 | 0.62 | ALDH1A1 (0.46) | ALOX5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL26981511 | 0.62 | KMT2A (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819699-A2 | DIAZEPINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056877-A2 | DIAZEPINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-06-01 | — | — | WO | disclosed |