Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5945170 | 0.83 | CYP2E1 (0.43) | CYP2E1 | |
| SCHEMBL3033079 | 0.79 | ALDH1A1 (0.43) | CYP2E1SMN1; SMN2 | |
| SCHEMBL5243546 | 0.78 | ALOX5 (0.31) | SMN1; SMN2 | |
| SCHEMBL3037813 | 0.78 | ALDH1A1 (0.45) | CYP2E1SMN1; SMN2 | |
| SCHEMBL5243502 | 0.77 | ALOX5 (0.30) | SMN1; SMN2 | |
| SCHEMBL3035256 | 0.74 | MAOA (0.64) | CYP2E1 | |
| Hydrochloric Acid SCHEMBL5839214 | 0.73 | CYP2E1 (0.54) | CYP2E1 | |
| SCHEMBL3037946 | 0.73 | DDB1 (0.43) | SMN1; SMN2 | |
| SCHEMBL5945198 | 0.72 | CYP2E1 (0.40) | CYP2E1SMN1; SMN2 | |
| SCHEMBL5622837 | 0.70 | ALDH1A1 (0.41) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105547-B2 | Antimicrobial 1-aryl dihydropyridone compounds | PHARMACIA AND UPJOHN COMPANY (US) | 2006-09-12 | — | — | US | disclosed |
| EP-1554273-A1 | ANTIMICROBIAL 1-ARYL DIHYDROPYRIDONE COMPOUNDS | Pharmacia & Upjohn Company LLC (US) | 2005-07-20 | — | — | EP | disclosed |
| US-20050070580-A1 | Antimicrobial 1-aryl dihydropyridone compounds | GORDEEV MIKHAIL FEDOR (US) | 2005-03-31 | — | — | US | disclosed |
| WO-2004033449-A1 | ANTIMICROBIAL 1-ARYL DIHYDROPYRIDONE COMPOUNDS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070580-A1 | Antimicrobial 1-aryl dihydropyridone compounds | TLR1, QDPR, AP1S1 | CYP2E1 1078/4885SMN1; SMN2 2518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.