Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | MIF | P14174 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244687 | 0.90 | BRD4 (0.44) | BRD4MIFNOTUM | |
| SCHEMBL5248779 | 0.89 | EPHX2 (0.35) | EPHX2BRD4MIFNOTUMNPC1 | |
| SCHEMBL5247112 | 0.88 | MLYCD (0.40) | BRD4NPC1RAB9A | |
| SCHEMBL3117550 | 0.87 | NOTUM (0.39) | EPHX2NOTUMPSEN1PSEN2APH1B | |
| SCHEMBL5249551 | 0.86 | NPC1 (0.40) | BRD4NPC1RAB9ADGAT1 | |
| SCHEMBL3111906 | 0.85 | SMPD1 (0.38) | BRD4NOTUMDGAT1 | |
| SCHEMBL5244665 | 0.84 | NOTUM (0.34) | EPHX2NOTUMPSEN1PSEN2APH1B | |
| SCHEMBL5249178 | 0.84 | SMPD1 (0.34) | BRD4NOTUMDGAT1 | |
| SCHEMBL5247054 | 0.84 | NOTUM (0.34) | NOTUMPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5245598 | 0.84 | GLS (0.44) | EPHX2MIFPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |