Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210788 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KMT2AMAPTLMNAPOLB | |
| SCHEMBL239465 | 0.82 | ALDH1A1 (0.66) | ALDH1A1KMT2AMAPTLMNAPOLB | |
| SCHEMBL22471423 | 0.82 | MAPT (0.59) | ALDH1A1KMT2AMAPTLMNAPOLB | |
| SCHEMBL5239681 | 0.80 | MAPT (0.38) | ALDH1A1MAPTLMNASMN1; SMN2TOP1 | |
| SCHEMBL28196822 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTLMNAPOLB | |
| SCHEMBL18876391 | 0.76 | MAPT (0.51) | ALDH1A1KMT2AMAPTLMNAPOLB | |
| SCHEMBL14851247 | 0.75 | MAPT (0.54) | ALDH1A1KMT2AMAPTLMNAPOLB | |
| SCHEMBL5242045 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPTLMNAPOLB | |
| SCHEMBL17422247 | 0.74 | MAPT (0.55) | ALDH1A1KMT2AMAPTLMNAPOLB | |
| SCHEMBL21373389 | 0.74 | MAPT (0.54) | ALDH1A1MAPTLMNASIRT6THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819699-A2 | DIAZEPINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056877-A2 | DIAZEPINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-06-01 | — | — | WO | disclosed |