SCHEMBL5244775

SCHEMBL5244775

COC(CCN1C(=O)NCC1CCCO[Si](C)(C)C(C)(C)C)OC

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5244981 0.73 DUT (0.41) DUT
SCHEMBL3535799 0.72 DUT (0.41) DUT
SCHEMBL21400915 0.67 DUT (0.40) DUT
SCHEMBL4032065 0.65 MEN1 (0.33)
SCHEMBL14690797 0.63 DUT (0.39) DUT
SCHEMBL14690796 0.63 DUT (0.39) DUT
SCHEMBL2287916 0.62 LMNA (0.40) DUT
SCHEMBL1712032 0.62 LMNA (0.40) DUT
SCHEMBL16180004 0.62 LMNA (0.40) DUT
SCHEMBL9410347 0.62 DUT (0.40) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1856049-A1 BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS Theravance, Inc. (US) 2007-11-21 EP disclosed
WO-2006099031-A1 BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS THERAVANCE, INC. (US) 2006-09-21 WO disclosed