Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246509 | 0.95 | NQO2 (0.37) | NQO2CYP19A1CNR2KDM4EALDH1A1 | |
| SCHEMBL5248944 | 0.80 | TDP1 (0.41) | NQO2CYP19A1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5245883 | 0.79 | NQO2 (0.39) | NQO2CYP19A1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5245517 | 0.76 | NQO2 (0.38) | NQO2CYP19A1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5249840 | 0.74 | NQO2 (0.39) | NQO2CYP19A1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5247849 | 0.73 | KDM4E (0.32) | NQO2CYP19A1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5246630 | 0.72 | NQO2 (0.40) | NQO2CYP19A1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5245502 | 0.70 | CA2 (0.42) | NQO2CYP19A1ALDH1A1EZH2 | |
| SCHEMBL98476 | 0.69 | ADRB2 (0.37) | NQO2CYP19A1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8920575 | 0.63 | HSD17B2 (0.52) | KDM4EALDH1A1HSD17B10TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |