Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 6/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | MPC2 | O95563 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245748 | 0.76 | NQO2 (0.41) | CA2PTPN1NQO2CYP19A1ALDH1A1 | |
| SCHEMBL5245517 | 0.72 | NQO2 (0.38) | NQO2CYP19A1ALDH1A1EZH2ADRB2 | |
| SCHEMBL5248944 | 0.72 | TDP1 (0.41) | NQO2CYP19A1ALDH1A1ADRB2ADRB1 | |
| SCHEMBL5249840 | 0.71 | NQO2 (0.39) | NQO2CYP19A1ALDH1A1MAPTEZH2 | |
| SCHEMBL5245883 | 0.71 | NQO2 (0.39) | NQO2CYP19A1ALDH1A1EZH2ADRB2 | |
| SCHEMBL8340297 | 0.70 | PTPN1 (0.48) | CA2PTPN1MAOACISD1MAOB | |
| SCHEMBL5245341 | 0.70 | NQO2 (0.36) | NQO2CYP19A1ALDH1A1EZH2 | |
| SCHEMBL5248487 | 0.70 | CA2 (0.42) | CA2PTPN1MAOACISD1MAOB | |
| SCHEMBL5246509 | 0.69 | NQO2 (0.37) | NQO2CYP19A1ALDH1A1EZH2 | |
| SCHEMBL5246630 | 0.68 | NQO2 (0.40) | NQO2CYP19A1ALDH1A1MAPTEZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |