Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 5/20 | 0.32 |
| ▸ | MPC2 | O95563 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12003019 | 0.79 | CA2 (0.36) | CA2MAPTPPARAPPARG | |
| SCHEMBL96163 | 0.70 | CA2 (0.46) | CA2MAPTMAOACISD1MAOB | |
| SCHEMBL5245502 | 0.70 | CA2 (0.42) | CA2MAPTADRB2ADRB1MAOA | |
| SCHEMBL97252 | 0.64 | CA2 (0.45) | CA2MAPTMAOACISD1PTPN1 | |
| SCHEMBL5249820 | 0.64 | ADRB2 (0.40) | ADRB2ADRB1CYP2C9KDM4ETSHR | |
| SCHEMBL6973500 | 0.63 | MAPT (0.51) | MAPTMAOACISD1MAOBFFAR1 | |
| SCHEMBL8172864 | 0.62 | MAOA (0.54) | MAPTMAOACISD1MAOBFFAR1 | |
| SCHEMBL8840901 | 0.62 | TSHR (0.61) | CA2MAPTMAOACISD1MAOB | |
| SCHEMBL16490038 | 0.62 | CA2 (0.54) | CA2PPARAPPARGMPC2CYP2C8 | |
| SCHEMBL7281232 | 0.62 | HTR2A (0.50) | MAPTADRB2ALDH1A1KDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |