Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 8/20 | 0.35 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244618 | 0.92 | TAS1R3 (0.33) | TAS1R3TAS1R1TAS1R2NAMPTTP53 | |
| SCHEMBL5244377 | 0.90 | BRD4 (0.38) | BRD4SMPD1 | |
| SCHEMBL5244782 | 0.88 | SMPD1 (0.36) | TAS1R3TAS1R1TAS1R2BRD4NAMPT | |
| SCHEMBL5248565 | 0.87 | BRD4 (0.36) | BRD4TP53SMPD1 | |
| SCHEMBL5247572 | 0.86 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2BRD4NAMPT | |
| SCHEMBL3120217 | 0.85 | BRD4 (0.39) | BRD4TP53SMPD1 | |
| SCHEMBL5246807 | 0.84 | BRD4 (0.38) | BRD4 | |
| SCHEMBL5243944 | 0.84 | SMPD1 (0.39) | BRD4TP53SMPD1 | |
| SCHEMBL5247498 | 0.84 | SMPD1 (0.39) | BRD4TP53SMPD1 | |
| SCHEMBL5244829 | 0.84 | BRD4 (0.37) | BRD4TP53SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |