Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 7/20 | 0.35 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246004 | 0.92 | TAS1R3 (0.34) | TAS1R3TAS1R1TAS1R2NAMPT | |
| SCHEMBL5244782 | 0.91 | SMPD1 (0.36) | TAS1R3TAS1R1TAS1R2BRD4NAMPT | |
| SCHEMBL5245879 | 0.86 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2BRD4NAMPT | |
| SCHEMBL5244312 | 0.84 | SMPD1 (0.35) | TAS1R3TAS1R1TAS1R2NAMPT | |
| SCHEMBL5244706 | 0.83 | ROCK2 (0.40) | BRD4 | |
| SCHEMBL5246767 | 0.83 | MIF (0.47) | BRD4 | |
| SCHEMBL3113676 | 0.83 | ACKR3 (0.41) | BRD4 | |
| SCHEMBL5248464 | 0.82 | BRD4 (0.35) | BRD4 | |
| SCHEMBL5244462 | 0.82 | MAPT (0.40) | BRD4 | |
| SCHEMBL5244426 | 0.82 | DRD2 (0.37) | BRD4NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |