Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.35 |
| ▸ | DDT | P30046 | 3/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246315 | 0.94 | HPGD (0.39) | PDE10AEPHX2ROCK2ROCK1HPGD | |
| SCHEMBL5244350 | 0.92 | ROCK2 (0.38) | PDE10ADDTPSEN1PSEN2APH1B | |
| SCHEMBL5244355 | 0.91 | PDE10A (0.40) | PDE10ADDTMETROCK2ROCK1 | |
| SCHEMBL5244804 | 0.89 | ROCK2 (0.39) | EPHX2DDTPSEN1PSEN2APH1B | |
| SCHEMBL5247821 | 0.89 | ROCK2 (0.40) | EPHX2METPSEN1PSEN2APH1B | |
| SCHEMBL5244821 | 0.89 | PPARG (0.38) | PDE10AEPHX2METROCK2ROCK1 | |
| SCHEMBL5245995 | 0.88 | ROCK2 (0.41) | EPHX2METROCK2ROCK1KLKB1 | |
| SCHEMBL3111267 | 0.87 | GLS (0.43) | EPHX2DDTPSEN1PSEN2APH1B | |
| SCHEMBL5246041 | 0.87 | MIF (0.45) | EPHX2DDTPSEN1PSEN2APH1B | |
| SCHEMBL5248109 | 0.87 | EGLN1 (0.38) | PDE10AEPHX2DDTPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |