Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.65 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1230760 | 0.80 | NPC1 (0.66) | HDAC8NPC1PKMKMT2AMAPT | |
| SCHEMBL6671653 | 0.79 | HDAC8 (1.00) | HDAC8AKR1C3NPC1PKMKAT6A | |
| SCHEMBL2830822 | 0.78 | HDAC8 (0.73) | HDAC8AKR1C3NPC1PKMMEN1 | |
| SCHEMBL7053842 | 0.78 | HDAC8 (0.73) | HDAC8AKR1C3NPC1PKMMEN1 | |
| SCHEMBL7053844 | 0.78 | HDAC8 (0.73) | HDAC8AKR1C3NPC1PKMMEN1 | |
| SCHEMBL31295303 | 0.78 | HDAC8 (0.73) | HDAC8AKR1C3NPC1PKMMEN1 | |
| SCHEMBL7152809 | 0.76 | FFAR1 (0.75) | HDAC8AKR1C3NPC1CASP3SENP7 | |
| SCHEMBL5246552 | 0.76 | HPGD (0.72) | HDAC8NPC1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL9671284 | 0.75 | AKR1C3 (0.62) | HDAC8AKR1C3NPC1CASP3SENP7 | |
| SCHEMBL8248607 | 0.75 | ALDH1A1 (0.72) | HDAC8AKR1C3NPC1PKMKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |