SCHEMBL5246569

SCHEMBL5246569

CCCC(NCC)C(CC)COC(N)=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.35
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 3/20 0.32
CYP3A4 P08684 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
ATM Q13315 1/20 0.32
LMNA P02545 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
HSD17B10 Q99714 1/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31
NFKB1 P19838 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5245068 0.86 CA1 (0.36) ALOX15CYP1A2CYP2D6PKMSMN1; SMN2
SCHEMBL5244904 0.85 ALOX15 (0.36) ALOX15CYP1A2CYP2D6PKMSMN1; SMN2
SCHEMBL5244845 0.77 CA2 (0.39) ALOX15CYP1A2CYP2D6PKMSMN1; SMN2
SCHEMBL6290111 0.76 LMNA (0.48) ALOX15CYP1A2CYP2D6PKMSMN1; SMN2
SCHEMBL6284462 0.75 CA1 (0.31) CA1CA2
SCHEMBL6251315 0.75 ALOX15 (0.39) ALOX15CYP1A2CYP2D6PKMSMN1; SMN2
SCHEMBL28162759 0.72 ALOX15 (0.43) ALOX15CYP1A2CYP2D6PKMSMN1; SMN2
SCHEMBL6289603 0.70 SMN1; SMN2 (0.44) ALOX15SMN1; SMN2TSHRCYP3A4TDP1
SCHEMBL5246727 0.70 EPHX1 (0.41) ALOX15CYP1A2TSHRCYP3A4TDP1
SCHEMBL6287229 0.70 CA2 (0.38) ALOX15TSHRCYP3A4TDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1379598-B1 UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS BASF AG (DE) 2007-09-12 EP disclosed
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed