Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | SELE | P16581 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5247221 | 0.80 | NR1H2 (0.50) | LMNAMAPTGFERALDH1A1SMN1; SMN2 | |
| SCHEMBL5246815 | 0.80 | LMNA (0.58) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL5247718 | 0.79 | CDC7 (0.57) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL5244234 | 0.79 | LMNA (0.56) | LMNAMAPTADORA2AADORA1ALDH1A1 | |
| SCHEMBL6213388 | 0.73 | MAPT (0.61) | LMNAMAPTGFERICAM1SELE | |
| SCHEMBL28946236 | 0.71 | LMNA (0.41) | LMNAMAPTGFERICAM1SELE | |
| SCHEMBL7059737 | 0.71 | MAPT (0.46) | LMNAMAPTGFERICAM1SELE | |
| SCHEMBL3063111 | 0.71 | LMNA (0.59) | LMNAMAPTGFERALDH1A1SMN1; SMN2 | |
| SCHEMBL12245875 | 0.69 | ACHE (0.57) | LMNAMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL83853 | 0.69 | ACHE (0.57) | LMNAMAPTALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101257948-A | Pyrimidine-fused diazepine derivatives and indole-fused pteridines | ATTENUON LLC (US) | 2008-09-03 | — | — | CN | disclosed |
| EP-1848506-A2 | PYRIMIDINE-FUSED DIAZEPINE DERIVATIVES AND INDOLE-FUSED PTERIDINES | Attenuon, LLC (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006089298-A2 | PYRIMIDINE-FUSED DIAZEPINE DERIVATIVES AND INDOLE-FUSED PTERIDINES | ATTENUON, LLC (US) | 2006-08-24 | — | — | WO | disclosed |