Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4835398 | 0.99 | SIGMAR1 (0.39) | SIGMAR1HRH3OPRD1CARM1PRMT6 | |
| SCHEMBL5248733 | 0.86 | TACR1 (0.37) | SIGMAR1HTR2CPYCR1 | |
| SCHEMBL5244849 | 0.86 | TACR1 (0.37) | SIGMAR1HTR2CCYP3A4PYCR1SLC6A2 | |
| SCHEMBL5245183 | 0.86 | TACR1 (0.37) | SIGMAR1HTR2COPRM1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL4834834 | 0.85 | TACR1 (0.36) | HTR2CSLC6A2SLC6A4KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4830193 | 0.85 | TACR1 (0.36) | SIGMAR1PYCR1 | |
| Hydrochloric Acid SCHEMBL4834561 | 0.85 | TACR1 (0.36) | SIGMAR1HTR2CSLC6A2SLC6A4 | |
| SCHEMBL5250554 | 0.84 | SLC6A4 (0.45) | SIGMAR1GAAHTR2COPRM1ALDH1A1 | |
| SCHEMBL5248023 | 0.83 | TACR1 (0.42) | CYP3A4 | |
| Hydrochloric Acid SCHEMBL4827379 | 0.83 | SLC6A4 (0.44) | SIGMAR1GAAHTR2COPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100467458-C | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB CO LTD (FR) | 2009-03-11 | — | — | CN | disclosed |
| WO-2006103342-A9 | INDANYL-PIPERAZINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2007-10-25 | — | — | WO | disclosed |
| EP-1707564-B1 | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2007-09-12 | — | — | EP | disclosed |
| EP-1707564-A2 | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2006-10-04 | — | — | EP | disclosed |
| CN-1840527-A | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2006-10-04 | — | — | CN | disclosed |