Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4827379 | 0.99 | SLC6A4 (0.44) | SLC6A4SLC6A2OPRM1OPRL1HTR2C | |
| SCHEMBL5248023 | 0.91 | TACR1 (0.42) | TACR1 | |
| Hydrochloric Acid SCHEMBL4830251 | 0.90 | TACR1 (0.41) | TACR1 | |
| SCHEMBL5245485 | 0.88 | TACR1 (0.43) | SLC6A4TACR1 | |
| Hydrochloric Acid SCHEMBL4835695 | 0.87 | TACR1 (0.43) | SLC6A4TACR1 | |
| SCHEMBL5249405 | 0.84 | SIGMAR1 (0.40) | SLC6A4SLC6A2OPRM1HTR2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL4835398 | 0.83 | SIGMAR1 (0.39) | SLC6A4SLC6A2OPRM1HTR2CALDH1A1 | |
| SCHEMBL5245183 | 0.81 | TACR1 (0.37) | SLC6A4SLC6A2OPRM1OPRL1HTR2C | |
| Hydrochloric Acid SCHEMBL4834834 | 0.80 | TACR1 (0.36) | SLC6A4SLC6A2HTR2CTACR1MEN1 | |
| SCHEMBL5245187 | 0.80 | SLC6A4 (0.46) | SLC6A4SLC6A2OPRM1OPRL1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1707564-B1 | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2007-09-12 | — | — | EP | disclosed |