Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | DDT | P30046 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3111267 | 0.93 | GLS (0.43) | GLSPOLBROCK2ROCK1DDT | |
| SCHEMBL5246401 | 0.91 | BRD4 (0.41) | NAMPTHTR7LMNAPOLBTP53 | |
| SCHEMBL5248109 | 0.88 | EGLN1 (0.38) | NAMPTHTR7GLSROCK2ROCK1 | |
| SCHEMBL3104911 | 0.88 | S1PR1 (0.41) | — | |
| SCHEMBL5246041 | 0.86 | MIF (0.45) | GLSLMNADDT | |
| SCHEMBL3102931 | 0.86 | TP53 (0.39) | LMNATP53SMN1; SMN2MAPT | |
| SCHEMBL5246077 | 0.86 | MMP13 (0.37) | TP53SMN1; SMN2THRBMAPTDDT | |
| SCHEMBL5244507 | 0.85 | BRD4 (0.40) | NAMPTLMNAPOLBSMN1; SMN2ROCK2 | |
| SCHEMBL5247715 | 0.85 | GLS (0.45) | GLSPOLBROCK2ROCK1DDT | |
| SCHEMBL5249581 | 0.85 | PSEN1 (0.42) | GLSROCK2ROCK1DDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |