Phenylboronic Acid

Phenylboronic Acid

SCHEMBL524828

C=C(C)C(N)=O.OB(O)c1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 0.56
CA4 P22748 1/20 0.56
CA6 P23280 1/20 0.56
CA5A P35218 1/20 0.56
CA7 P43166 1/20 0.56
CA14 Q9ULX7 1/20 0.56
CA5B Q9Y2D0 1/20 0.56
TDP1 Q9NUW8 2/20 0.48
CA2 P00918 4/20 0.43
CA1 P00915 3/20 0.43
MGLL Q99685 2/20 0.43
PCSK9 Q8NBP7 1/20 0.39
ORAI1 Q96D31 1/20 0.39
ORAI2 Q96SN7 1/20 0.39
ORAI3 Q9BRQ5 1/20 0.39
TRPV6 Q9H1D0 1/20 0.39
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 1/20 0.39
P4HB P07237 1/20 0.39
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylboronic Acid SCHEMBL1712456 0.88 ENPP2 (0.61) ENPP2CA4CA6CA5ACA7
Phenylboronic Acid SCHEMBL28704052 0.87 ENPP2 (0.67) ENPP2CA4CA6CA5ACA7
Phenylboronic Acid SCHEMBL23824843 0.83 ENPP2 (0.74) ENPP2CA4CA6CA5ACA7
Phenylboronic Acid SCHEMBL28944102 0.83 ENPP2 (0.74) ENPP2CA4CA6CA5ACA7
Phenylboronic Acid SCHEMBL6701482 0.83 ENPP2 (0.74) ENPP2CA4CA6CA5ACA7
SCHEMBL28420557 0.80 PARP1 (0.44) ENPP2TDP1CA2MGLLKDM4E
Biphenyl SCHEMBL7764468 0.79 TDP1 (0.57) TDP1KDM4EALDH1A1POLBCYP3A4
Phenylboronic Acid SCHEMBL17202516 0.78 ENPP2 (0.82) ENPP2CA4CA6CA5ACA7
Phenylboronic Acid SCHEMBL1723445 0.78 CA4 (0.58) ENPP2CA4CA6CA5ACA7
Benzene SCHEMBL28099155 0.78 TDP1 (0.80) TDP1KDM4EALDH1A1POLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109082126-B Glucose response driven hydrogel multistage motor and preparation method thereof 华南理工大学 2021-02-12 CN claimed
CN-109082126-B Glucose response driven hydrogel multistage motor and preparation method thereof 华南理工大学 2021-02-12 CN disclosed
WO-2019188653-A1 PHOTOSENSITIVE COMPOSITION 富士フイルム株式会社 2019-10-03 WO disclosed
EP-2578234-B1 MEDICINE ADMINISTERING DEVICE COMPRISING A SUGAR REPSONSIVE GEL NAT INST FOR MATERIALS SCIENCE (JP) 2017-07-12 EP disclosed
EP-2522679-B1 PHENYLBORONIC ACID MONOMER AND PHENYLBORONIC ACID POLYMER NAT INST FOR MATERIALS SCIENCE (JP) 2016-07-13 EP disclosed
US-8979261-B2 Silicone hydrogel ophthalmic devices molded in vinyl alcohol copolymer molds and related methods COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2015-03-17 US disclosed
US-20130176530-A1 Silicone Hydrogel Ophthalmic Devices Molded In Vinyl Alcohol Copolymer Molds And Related Methods COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2013-07-11 US disclosed
EP-2598318-A1 SILICONE HYDROGEL OPHTHALMIC DEVICES MOLDED IN VINYL ALCOHOL COPOLYMER MOLDS AND RELATED METHODS CooperVision International Holding Company, LP (BB) 2013-06-05 EP disclosed
EP-2578234-A1 SUGAR RESPONSIVE GEL AND MEDICINE ADMINISTERING DEVICE National Institute for Materials Science (JP) 2013-04-10 EP disclosed
US-20130066264-A1 SUGAR-RESPONSIVE GEL AND MEDICINE ADMINISTERING DEVICE NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) 2013-03-14 US disclosed
US-20120283403-A1 Phenylboronic Acid Monomer and Phenylboronic Acid Polymer NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) 2012-11-08 US disclosed
US-20120097540-A1 MATERIALS AND METHODS FOR RESOLVING POLYHYDRIC SPECIES BY ELECTROPHORESIS JAMES TONY DAVID (GB) 2012-04-26 US disclosed
WO-2012042213-A1 NOVEL INTERACTION BETWEEN STAPHYLOCOCCUS AUREUS SBI AND C3D PROTEINS BATH VENTURES (GB) 2012-04-05 WO disclosed
WO-2012013947-A1 SILICONE HYDROGEL OPHTHALMIC DEVICES MOLDED IN VINYL ALCOHOL COPOLYMER MOLDS AND RELATED METHODS GOODENOUGH NEIL (GB) 2012-02-02 WO disclosed
US-7988988-B2 Contact lenses with mucin affinity BAUSCH & LOMB INCORPORATED (US) 2011-08-02 US disclosed
EP-2344885-A2 MATERIALS AND METHODS FOR RESOLVING POLYHYDRIC SPECIES BY ELECTROPHORESIS The University of Bath (GB) 2011-07-20 EP disclosed
WO-2010041037-A2 MATERIALS AND METHODS FOR RESOLVING POLYHYDRIC SPECIES BY ELECTROPHORESIS THE UNIVERSITY OF BATH (GB) 2010-04-15 WO disclosed
EP-1968658-A2 CONTACT LENSES WITH MUCIN AFFINITY BAUSCH & LOMB INCORPORATED (US) 2008-09-17 EP disclosed
WO-2007061919-A2 CONTACT LENSES WITH MUCIN AFFINITY BAUSCH & LOMB INCORPORATED (US) 2007-05-31 WO disclosed
US-20070116740-A1 Contact lenses with mucin affinity BAUSCH & LOMB INCORPORATED 2007-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120283403-A1 Phenylboronic Acid Monomer and Phenylboronic Acid Polymer MAPK13, PAH, MAP3K13 ENPP2 2601/4885CA4 2444/4885CA6 415/4885
US-20130066264-A1 SUGAR-RESPONSIVE GEL AND MEDICINE ADMINISTERING DEVICE GCKR, GPR119, GCK ENPP2 1330/4885CA4 1718/4885CA6 941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.