Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3320865 | 0.82 | TRPV1 (0.57) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL18235941 | 0.80 | KMT2A (0.54) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL4011536 | 0.76 | LDHA (0.78) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL12510067 | 0.76 | KMT2A (0.59) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL5798843 | 0.75 | RAB9A (0.65) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL12233592 | 0.73 | KMT2A (0.59) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL18415605 | 0.73 | PTPN1 (0.55) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL14554346 | 0.73 | TRPV1 (0.62) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL3319497 | 0.72 | RAB9A (0.47) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL15228759 | 0.72 | RAB9A (0.62) | TRPV1RAB9ANPC1CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861384-A1 | 11-BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS | Sterix Limited (GB) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006100502-A1 | 11-BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS | STERIX LIMITED (GB) | 2006-09-28 | — | — | WO | disclosed |