Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL5348855 | 0.98 | GPR3 (0.32) | GPR3 | |
| Cyclopentane SCHEMBL6557619 | 0.97 | BCHE (0.33) | GPR3 | |
| Fluoride Ion SCHEMBL1130995 | 0.97 | GPR3 (0.33) | GPR3 | |
| Hydrochloric Acid SCHEMBL7180983 | 0.95 | GPR3 (0.31) | GPR3 | |
| Hydrochloric Acid SCHEMBL7621841 | 0.95 | GPR3 (0.31) | GPR3 | |
| Propene SCHEMBL27558553 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL7168371 | 0.91 | CHRNB2 (0.30) | — | |
| Phenol SCHEMBL4443006 | 0.89 | — | — | |
| Methane SCHEMBL7940242 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL7717104 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 634 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110922517-B | Ethylene copolymer and preparation method thereof | 中国石油化工股份有限公司 | 2023-01-03 | — | — | CN | claimed |
| US-10618987-B2 | Modified catalyst supports | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2020-04-14 | — | — | US | claimed |
| US-20190161565-A1 | Modified Catalyst Supports | TOTAL RES & TECHNOLOGY FELUY (BE) | 2019-05-30 | — | — | US | claimed |
| US-10233268-B2 | Modified catalyst supports | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2019-03-19 | — | — | US | claimed |
| US-8445607-B2 | Process for the preparation of a particulate bimodal polyethylene product | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2013-05-21 | — | — | US | claimed |
| EP-2513163-A1 | PROCESS FOR THE PREPARATION OF A PARTICULATE BIMODAL POLYETHYLENE PRODUCT | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2012-10-24 | — | — | EP | claimed |
| US-20120245307-A1 | PROCESS FOR THE PREPARATION OF A PARTICULATE BIMODAL POLYETHYLENE PRODUCT | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2012-09-27 | — | — | US | claimed |
| EP-2160233-A1 | PROCESS FOR THE POLYMERISATION OF OLEFINS | Total Petrochemicals Research Feluy (BE) | 2010-03-10 | — | — | EP | claimed |
| US-20090105433-A1 | Multi-component catalyst systems and polymerization processes for forming in-situ heterophasic copolymers and/or varying the xylene solubles content of polyolefins | FINA TECHNOLOGY, INC. (US) | 2009-04-23 | — | — | US | claimed |
| WO-2009000782-A1 | PROCESS FOR THE POLYMERISATION OF OLEFINS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-12-31 | — | — | WO | claimed |
| US-6468936-B1 | MIXTURE OF AN ALUMINOXANE AND A METALLOCENE; REDUCES REACTOR FOULING AND GIVES A POLYMER HAVING HIGH BULK DENSITY; EFFECTIVE FOR BOTH ISOSPECIFIC AND SYNDIOSPECIFIC POLYMERIZATION | FINA TECHNOLOGY, INC. | 2002-10-22 | — | — | US | claimed |
| CN-1277972-A | Deactivation of inert particle material for single point catalyst used for prodn. of EPDM | UNINON CARBIDE CHEMICALS & PLA (US) | 2000-12-27 | — | — | CN | claimed |
| EP-0523416-B1 | Catalyst and process for preparing high molecular weight polyolefines | TARGOR GMBH (DE) | 1999-10-20 | — | — | EP | claimed |
| US-5914376-A | Catalyst for the polymerization of olefins, process for the preparation thereof, and use thereof | TARGOR GMBH (DE) | 1999-06-22 | — | — | US | claimed |
| US-5776851-A | COORDINATION POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 1998-07-07 | — | — | US | claimed |
| US-5696045-A | USING MIXTURE OF ZIRCONOCENE CATALYSTS | TARGOR GMBH (DE) | 1997-12-09 | — | — | US | claimed |
| US-5637400-A | POLYMERIZATION USING ALUMINOXANE OR METALLOCENE CATALYSTS; OPTICAL WAVEGUIDES, OPTICAL FIBERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-10 | — | — | US | claimed |
| EP-0705851-A2 | Catalyst systems and process for producing broad molecular weight distribution polyolefin | PHILLIPS PETROLEUM COMPANY (US) | 1996-04-10 | — | — | EP | claimed |
| EP-0516019-B1 | Process for preparing syndiotactic polyolefins with large molecular weight distribution | HOECHST AG (DE) | 1995-12-27 | — | — | EP | claimed |
| US-5371158-A | Bulk polymerization using specific metallocene catalysts for the preparation of cycloolefin polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | claimed |