Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 8/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244774 | 0.90 | ACHE (0.49) | ALOX15ACHEMMP9MMP8MMP14 | |
| SCHEMBL5244887 | 0.88 | EPHX1 (0.44) | CA1CA2ALOX15CHRNB2CHRNA4 | |
| SCHEMBL5244825 | 0.86 | ALOX15 (0.41) | SMN1; SMN2CA1CA2ALOX15CHRNB2 | |
| SCHEMBL5248499 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2CA1CA2ALOX15CHRNB2 | |
| SCHEMBL5247868 | 0.82 | CA2 (0.40) | SMN1; SMN2CA1CA2ALOX15TSHR | |
| SCHEMBL5249428 | 0.81 | ACHE (0.47) | ALOX15ACHEMMP9MMP8MMP14 | |
| SCHEMBL5244752 | 0.80 | EPHX1 (0.41) | CA1CA2ALOX15CHRNB2CHRNA4 | |
| SCHEMBL5244912 | 0.79 | ACHE (0.49) | ALOX15ACHEMMP9MMP8MMP14 | |
| SCHEMBL6289603 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2CA1CA2ALOX15CHRNB2 | |
| SCHEMBL6290130 | 0.77 | EPHX1 (0.37) | CA1CA2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379598-B1 | UNSATURATED COMPOUNDS CONTAINING CARBAMATE TERMINAL GROUPS OR UREA TERMINAL GROUPS | BASF AG (DE) | 2007-09-12 | — | — | EP | disclosed |
| US-6916854-B2 | Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040097642-A1 | Unsaturated compounds containing carbamate terminal groups or urea terminal groups | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |