Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | STAT6 | P42226 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800522 | 0.78 | GRIN2D (0.30) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Bicarbonate SCHEMBL7732730 | 0.72 | EPHX1 (0.35) | SIGMAR1TSHRPOLBTHRB | |
| SCHEMBL6860792 | 0.70 | LMNA (0.43) | SIGMAR1LMNASLC22A2SLC22A1GRIN2D | |
| Hydrochloric Acid SCHEMBL28004256 | 0.69 | LMNA (0.46) | SIGMAR1LMNASLC22A2SLC22A1GRIN2D | |
| SCHEMBL11678107 | 0.68 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL1497426 | 0.67 | LMNA (0.40) | SIGMAR1LMNASLC22A2SLC22A1GRIN2D | |
| SCHEMBL11677852 | 0.65 | ALDH1A1 (0.30) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6860339 | 0.65 | LMNA (0.48) | SIGMAR1LMNASLC22A2SLC22A1GRIN2D | |
| SCHEMBL15922703 | 0.65 | EPHX1 (0.35) | SIGMAR1LMNASLC22A2SLC22A1GRIN2D | |
| SCHEMBL294644 | 0.65 | EPHX1 (0.35) | SIGMAR1LMNASLC22A2SLC22A1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838297-A1 | 1-AMINOCYCLOHEXANE-DERIVATIVES FOR THE TREATMENT OF MULTIPLE SCLEROSIS EMOTIONAL LABILITY AND PSEUDOBULBAR AFFECT | Merz Pharma GmbH & Co. KGaA (DE) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006069294-A1 | 1-AMINOCYCLOHEXANE-DERIVATIVES FOR THE TREATMENT OF MULTIPLE SCLEROSIS EMOTIONAL LABILITY AND PSEUDOBULBAR AFFECT | MERZ PHARMA GMBH & CO. KGAA (DE) | 2006-06-29 | — | — | WO | disclosed |