Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 3/20 | 0.44 |
| ▸ | GABRD | O14764 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.44 |
| ▸ | GABRE | P78334 | 3/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15380562 | 0.83 | MKNK1 (0.44) | NAPRTHTTHSD17B10GABRPGABRD | |
| SCHEMBL5355271 | 0.81 | NAPRT (0.47) | NAPRTHSD17B10GABRPGABRDGABRA1 | |
| SCHEMBL19857454 | 0.81 | NAPRT (0.57) | NAPRTHTTHSD17B10GABRPGABRD | |
| SCHEMBL29860445 | 0.81 | KDM4E (0.50) | NAPRTHTTHSD17B10GABRPGABRD | |
| SCHEMBL1243693 | 0.81 | KDM4E (0.50) | NAPRTHTTHSD17B10GABRPGABRD | |
| SCHEMBL11895139 | 0.79 | NAPRT (0.46) | NAPRTHTTHSD17B10GABRPGABRD | |
| SCHEMBL3426148 | 0.79 | NAPRT (0.46) | NAPRTHTTHSD17B10GABRPGABRD | |
| SCHEMBL5249643 | 0.79 | NAPRT (0.46) | NAPRTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11819966 | 0.79 | NAPRT (0.46) | NAPRTHSD17B10GABRPGABRDGABRA1 | |
| SCHEMBL1260539 | 0.79 | NOS2 (0.52) | NAPRTGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020233676-A1 | AMIDE-SUBSTITUTED IMIDAZO COMPOUNDS AS SELECTIVE INHIBITORS OF INDOLEAMINE 2, 3-DIOXYGENASES | BEIGENE, LTD. (KY) | 2020-11-26 | — | — | WO | disclosed |
| CN-102718745-A | Novel amino pyridine compound, its preparation method, pharmaceutical composition containing compound and application thereof | SHANGHAI INST MATERIA MEDICA | 2012-10-10 | — | — | CN | disclosed |