Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96673 | 0.82 | IDE (0.38) | IDEALDH1A1KMT2AMEN1HTT | |
| SCHEMBL96785 | 0.76 | SLC9A1 (0.38) | KMT2AMEN1HTTLMNA | |
| SCHEMBL20711258 | 0.75 | IDE (0.45) | IDEALDH1A1KMT2AMEN1HTT | |
| SCHEMBL3032401 | 0.73 | KMT2A (0.34) | ALDH1A1KMT2AMEN1NAALAD2LMNA | |
| SCHEMBL20711367 | 0.73 | CNR2 (0.49) | IDEALDH1A1KMT2AMEN1HTT | |
| SCHEMBL6110896 | 0.72 | IDE (0.41) | IDEALDH1A1KMT2AMEN1HTT | |
| SCHEMBL4916117 | 0.71 | IDE (0.40) | IDEALDH1A1KMT2AMEN1HTT | |
| SCHEMBL6473514 | 0.70 | ALDH1A1 (0.38) | IDEALDH1A1KMT2AMEN1HTT | |
| SCHEMBL3033831 | 0.69 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1HTTGAA | |
| SCHEMBL3015911 | 0.67 | SLC9A1 (0.36) | ALDH1A1KMT2AMEN1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |