Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3113152 | 0.94 | SLC6A5 (0.42) | SLC6A5MAPK11MAPK14CHRM4MEN1 | |
| SCHEMBL5244846 | 0.87 | SLC6A5 (0.37) | SLC6A5CHRM4MEN1KMT2AHPGDS | |
| SCHEMBL3112209 | 0.87 | SLC6A5 (0.40) | SLC6A5MAPK11MAPK14CHRM4HPGDS | |
| Trifluoroacetic Acid SCHEMBL5247595 | 0.86 | SLC6A5 (0.51) | SLC6A5CHRM4MEN1KMT2A | |
| SCHEMBL3118328 | 0.85 | BRD4 (0.42) | MAPK11MAPK14MAPTCHRM4BRD4 | |
| SCHEMBL5250048 | 0.84 | EPHX2 (0.46) | MAPK14MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5247913 | 0.84 | DRD2 (0.49) | SLC6A5CHRM4 | |
| SCHEMBL3113582 | 0.83 | HPGD (0.42) | MEN1KMT2A | |
| SCHEMBL3111992 | 0.83 | SPHK2 (0.45) | MEN1KMT2AGABRA5BRD4 | |
| SCHEMBL5245587 | 0.83 | RAB9A (0.49) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |