Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.50 |
| ▸ | CES1 | P23141 | 5/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683035 | 0.87 | CES2 (0.44) | CES2CES1SRCALBBCHE | |
| SCHEMBL5255790 | 0.86 | CES2 (0.43) | CES2CES1SRCITGB2ICAM1 | |
| SCHEMBL6873558 | 0.86 | CES2 (0.43) | CES2CES1SRCALBBCHE | |
| SCHEMBL4076713 | 0.80 | GPR35 (0.44) | CES2CES1TTRKMT2AALDH1A1 | |
| SCHEMBL4076707 | 0.80 | GPR35 (0.44) | CES2CES1TTRKMT2AALDH1A1 | |
| SCHEMBL7492198 | 0.79 | CES2 (0.41) | CES2CES1SRCBCHEALDH1A1 | |
| SCHEMBL1669003 | 0.79 | CES2 (0.64) | CES2CES1ALBBCHETTR | |
| SCHEMBL1669004 | 0.79 | CES2 (0.64) | CES2CES1ALBBCHETTR | |
| SCHEMBL30428173 | 0.79 | CES2 (0.48) | CES2CES1ALBBCHETTR | |
| SCHEMBL22862585 | 0.77 | CES2 (0.47) | CES2CES1ALBBCHETTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1431299-B1 | IMIDAZO(1,2-a)PYRIMIDINES AND FUNGICIDE COMPOSITIONS CONTAINING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2007-05-23 | — | — | EP | disclosed |
| US-7211545-B2 | Imidazo[1,2-a]pyrimidine and fungicidal compositions containing thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-01 | — | — | US | disclosed |
| US-20040235865-A1 | Imidazo[1,2-a]pyrimidine and fungicidal compositions containing thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-25 | — | — | US | disclosed |
| US-20040162428-A1 | 6-(2,6-difluorophenyl)-triazolopyrimidines as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-19 | — | — | US | disclosed |
| EP-1431299-A1 | IMIDAZO(1,2-a)PYRIMIDINES AND FUNGICIDE COMPOSITIONS CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2004-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162428-A1 | 6-(2,6-difluorophenyl)-triazolopyrimidines as fungicides | CBR3, CBR1, CNPY2 | CES2 649/4885CES1 1377/4885SRC 909/4885 |
| US-20040235865-A1 | Imidazo[1,2-a]pyrimidine and fungicidal compositions containing thereof | CBR1, NAT1, CBR3 | CES2 1472/4885CES1 419/4885SRC 4249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.