Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5254396 | 0.88 | MAPK1 (0.39) | CES2CES1ITGB2ICAM1ITGAL | |
| SCHEMBL5250437 | 0.87 | CES2 (0.50) | CES2CES1SRCALBLMNA | |
| SCHEMBL7676477 | 0.85 | AKR1C3 (0.41) | CES2CES1 | |
| SCHEMBL7479581 | 0.84 | CES2 (0.44) | CES2CES1ALBBCHEITGB2 | |
| SCHEMBL8209123 | 0.78 | CES2 (0.44) | CES2CES1SRCLMNASMN1; SMN2 | |
| SCHEMBL6873558 | 0.78 | CES2 (0.43) | CES2CES1SRCALBLMNA | |
| SCHEMBL1723267 | 0.77 | NLRP3 (0.43) | CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL13170115 | 0.75 | CES2 (0.62) | CES2CES1ALBLMNABCHE | |
| SCHEMBL15645990 | 0.75 | CES2 (0.47) | CES2CES1ALBLMNASMN1; SMN2 | |
| SCHEMBL15645912 | 0.75 | CES2 (0.47) | CES2CES1ALBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |