Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334176 | 0.85 | TSHR (0.50) | TSHRMAPTPOLBGAAALDH1A1 | |
| SCHEMBL7532164 | 0.85 | MAPT (0.50) | TSHRMAPTALDH1A1TDP1EPHX2 | |
| SCHEMBL8167955 | 0.84 | MAPT (0.53) | MAPTALDH1A1EPHX2DGKALMNA | |
| SCHEMBL30529014 | 0.83 | TSHR (0.48) | TSHRMAPTPOLBGAAALDH1A1 | |
| SCHEMBL27561555 | 0.83 | TSHR (0.48) | TSHRMAPTPOLBGAAALDH1A1 | |
| SCHEMBL10401223 | 0.83 | TSHR (0.55) | TSHRMAPTPOLBGAAALDH1A1 | |
| SCHEMBL846984 | 0.82 | EGLN1 (0.45) | TSHRMAPTPOLBGAAALDH1A1 | |
| SCHEMBL3968791 | 0.82 | TSHR (0.48) | TSHRMAPTPOLBGAAALDH1A1 | |
| SCHEMBL42941 | 0.81 | MAPT (0.59) | TSHRMAPTALDH1A1TDP1EPHX2 | |
| SCHEMBL356035 | 0.81 | MAPT (0.53) | TSHRMAPTPOLBGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103052638-B | Prepare the method for dimiracetam | NEUROTUNE AG (CH) | 2015-09-30 | — | — | CN | disclosed |
| EP-2598504-B1 | PROCESS FOR THE PREPARATION OF DIMIRACETAM | NEUROTUNE AG (CH) | 2014-04-16 | — | — | EP | disclosed |
| EP-2598504-B1 | PROCESS FOR THE PREPARATION OF DIMIRACETAM | NEUROTUNE AG (CH) | 2014-04-16 | — | — | EP | disclosed |
| US-8476453-B2 | Process for the preparation of dimiracetam | NEUROTUNE AG (CH) | 2013-07-02 | — | — | US | disclosed |
| US-8476453-B2 | Process for the preparation of dimiracetam | NEUROTUNE AG (CH) | 2013-07-02 | — | — | US | disclosed |
| US-8476453-B2 | Process for the preparation of dimiracetam | NEUROTUNE AG (CH) | 2013-07-02 | — | — | US | disclosed |
| EP-2598504-A1 | PROCESS FOR THE PREPARATION OF DIMIRACETAM | Neurotune AG (CH) | 2013-06-05 | — | — | EP | disclosed |
| US-20130123509-A1 | PROCESS FOR THE PREPARATION OF DIMIRACETAM | NEUROTUNE AG (CH) | 2013-05-16 | — | — | US | disclosed |
| US-20130123509-A1 | PROCESS FOR THE PREPARATION OF DIMIRACETAM | NEUROTUNE AG (CH) | 2013-05-16 | — | — | US | disclosed |
| US-20130123509-A1 | PROCESS FOR THE PREPARATION OF DIMIRACETAM | NEUROTUNE AG (CH) | 2013-05-16 | — | — | US | disclosed |
| CN-103052638-A | Process for the preparation of dimiracetam | NEUROTUNE AG | 2013-04-17 | — | — | CN | disclosed |
| WO-2012013640-A1 | PROCESS FOR THE PREPARATION OF DIMIRACETAM | NEUROTUNE AG (CH) | 2012-02-02 | — | — | WO | disclosed |
| WO-2012013640-A1 | PROCESS FOR THE PREPARATION OF DIMIRACETAM | NEUROTUNE AG (CH) | 2012-02-02 | — | — | WO | disclosed |
| US-5200406-A | Nootropic agents; learning enhancement | I.S.F. SOCIETA PER AZIONI (IT) | 1993-04-06 | — | — | US | disclosed |
| US-5130319-A | Cognition activators for memory disorders | I.S.F. SOCIETA PER AZIONI (IT) | 1992-07-14 | — | — | US | disclosed |
| US-5053422-A | Learning-memory enhancers; nootropic agents | I.S.F. SOCIETA PER AZIONI (IT) | 1991-10-01 | — | — | US | disclosed |
| CN-1036204-A | some compounds | ISF SPA (IT) | 1989-10-11 | — | — | CN | disclosed |
| EP-0335483-A2 | Condensed imidazole derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them. | ISF SOCIETA PER AZIONI (IT) | 1989-10-04 | — | — | EP | disclosed |
| EP-0208272-A2 | Method for the preparation of alkyl esters of 3,4-epoxybutyric acid | TECNOPART S.r.l. (IT) | 1987-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123509-A1 | PROCESS FOR THE PREPARATION OF DIMIRACETAM | ADH1A, ADH1C, OGDH | TSHR 3699/4885MAPT 729/4885POLB 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.