Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.70 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.70 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 2/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1926470 | 0.90 | LMNA (0.55) | PDCD1CD274SMN1; SMN2SCN1ASCN2A | |
| SCHEMBL525077 | 0.90 | LMNA (0.55) | PDCD1CD274SMN1; SMN2SCN1ASCN2A | |
| SCHEMBL570078 | 0.88 | PDCD1 (0.72) | PDCD1CD274SLC1A5SMN1; SMN2KDM4E | |
| SCHEMBL7615892 | 0.88 | CYP4F2 (0.55) | PDCD1CD274KDM4EMAPTL3MBTL1 | |
| SCHEMBL25615625 | 0.87 | PDCD1 (0.70) | PDCD1CD274SLC1A5SMN1; SMN2KDM4E | |
| SCHEMBL12724883 | 0.85 | PDCD1 (0.68) | PDCD1CD274SLC1A5SMN1; SMN2KDM4E | |
| SCHEMBL855278 | 0.84 | MAPT (0.51) | PDCD1CD274SMN1; SMN2MAPTSCN1A | |
| SCHEMBL296543 | 0.82 | PDCD1 (1.00) | PDCD1CD274SLC1A5SMN1; SMN2KDM4E | |
| SCHEMBL20682164 | 0.81 | PDCD1 (0.57) | PDCD1CD274SLC1A5SMN1; SMN2KDM4E | |
| SCHEMBL2838336 | 0.81 | CA12 (0.67) | PDCD1CD274SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306145-A1 | Preparation Of Ginkgolide And F-Seco-Ginkgolide Lactols | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-12-11 | — | — | US | disclosed |
| WO-2006083366-A2 | PREPARATION OF GINKGOLIDE AND F-SECO-GINKGOLIDE LACTOLS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2006-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306145-A1 | Preparation Of Ginkgolide And F-Seco-Ginkgolide Lactols | GID4, GALK1, GGPS1 | PDCD1 3150/4885CD274 2886/4885SLC1A5 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.