Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250048 | 0.89 | EPHX2 (0.46) | SMN1; SMN2MEN1KMT2AHPGDLMNA | |
| SCHEMBL5249014 | 0.88 | CCR1 (0.45) | SMN1; SMN2MEN1KMT2AHPGDLMNA | |
| SCHEMBL5248465 | 0.87 | CCR1 (0.46) | SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL5245586 | 0.87 | CCR1 (0.46) | MEN1KMT2AHPGDMAPTLMNA | |
| SCHEMBL5244893 | 0.86 | MAPK14 (0.48) | NAMPT | |
| SCHEMBL5244539 | 0.86 | SMO (0.44) | SMN1; SMN2MEN1KMT2AHPGDMAPT | |
| SCHEMBL5249146 | 0.86 | CCR1 (0.51) | MEN1KMT2AMAPTTDP1NPSR1 | |
| SCHEMBL5244716 | 0.86 | CCR1 (0.57) | MEN1KMT2AMAPTTDP1LMNA | |
| SCHEMBL5247796 | 0.86 | CCR1 (0.45) | MEN1KMT2AHPGDMAPTPOLB | |
| SCHEMBL5247431 | 0.86 | RIPK1 (0.44) | SMN1; SMN2MEN1KMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |