Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | FABP1 | P07148 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | DBH | P09172 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | PARL | Q9H300 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524834 | 0.98 | MAPT (0.47) | MAPTKMT2ASMN1; SMN2FABP1SLC22A6 | |
| SCHEMBL514247 | 0.82 | SLC22A6 (0.53) | MAPTSMN1; SMN2FABP1SLC22A6TSHR | |
| Ammonia Solution, Strong SCHEMBL1278643 | 0.80 | SLC22A6 (0.52) | MAPTSMN1; SMN2FABP1SLC22A6TSHR | |
| SCHEMBL28288293 | 0.80 | SLC22A6 (0.52) | MAPTSMN1; SMN2FABP1SLC22A6TSHR | |
| SCHEMBL1882763 | 0.80 | SLC22A6 (0.52) | MAPTSMN1; SMN2FABP1SLC22A6MMP2 | |
| SCHEMBL27715562 | 0.76 | KDM4E (0.52) | MAPTKMT2ASMN1; SMN2FABP1SLC22A6 | |
| SCHEMBL9985549 | 0.75 | ALDH1A1 (0.59) | MAPTKMT2ASMN1; SMN2ALDH1A1HTR6 | |
| SCHEMBL3827901 | 0.74 | SLC22A6 (0.47) | MAPTKMT2ASMN1; SMN2FABP1SLC22A6 | |
| SCHEMBL235067 | 0.74 | HSD11B1 (0.50) | MAPTKMT2ASMN1; SMN2FABP1SLC22A6 | |
| SCHEMBL29382842 | 0.74 | HSD11B1 (0.50) | MAPTKMT2ASMN1; SMN2FABP1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598208-A2 | NEW USES | Evocutis plc (GB) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012013967-A2 | NEW USES | SYNTOPIX GROUP PLC (GB) | 2012-02-02 | — | — | WO | disclosed |