SCHEMBL525215

SCHEMBL525215

O=C(NCCO)C(CO)CO

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
USP2 O75604 2/20 0.61
MAPT P10636 2/20 0.61
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
TSHR P16473 2/20 0.48
CYP3A4 P08684 1/20 0.40
ALDH1A2 O94788 1/20 0.36
ALDH2 P05091 1/20 0.36
ALDH1A3 P47895 1/20 0.36
PTGS1 P23219 1/20 0.35
KCNH2 Q12809 1/20 0.35
HTT P42858 2/20 0.34
KDM4E B2RXH2 2/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CNR1 P21554 1/20 0.34
HDAC3 O15379 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9247132 0.97 ALDH1A1 (0.58) ALDH1A1USP2MAPTMEN1KMT2A
SCHEMBL6732293 0.81 ALDH1A1 (0.64) ALDH1A1USP2MAPTMEN1KMT2A
SCHEMBL2880184 0.80 ALDH1A1 (0.56) ALDH1A1USP2MAPTMEN1KMT2A
SCHEMBL14618454 0.78 USP2 (0.67) ALDH1A1USP2MAPTMEN1KMT2A
SCHEMBL10476199 0.77 USP2 (0.65) ALDH1A1USP2MAPTMEN1KMT2A
SCHEMBL2871448 0.77 ALDH1A1 (0.52) ALDH1A1USP2MAPTMEN1KMT2A
SCHEMBL8895535 0.76 USP2 (1.00) ALDH1A1USP2MAPTMEN1KMT2A
SCHEMBL14602775 0.76 USP2 (1.00) ALDH1A1USP2MAPTMEN1KMT2A
SCHEMBL3871043 0.76 USP2 (1.00) ALDH1A1USP2MAPTMEN1KMT2A
SCHEMBL16798146 0.75 ALDH1A1 (0.56) ALDH1A1USP2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1229940-A1 TEMPERATURE-CONTROLLED AND PH-DEPENDANT SELF-GELLING BIOPOLYMERIC AQUEOUS SOLUTION BIO SYNTECH CANADA INC. (CA) 2002-08-14 EP claimed
WO-2001036000-A1 TEMPERATURE-CONTROLLED AND PH-DEPENDANT SELF-GELLING BIOPOLYMERIC AQUEOUS SOLUTION BIO SYNTECH CANADA, INC. (CA) 2001-05-25 WO claimed
EP-0579138-B1 Process and reagent for specifically determining LDL in specimens from serum BOEHRINGER MANNHEIM GMBH (DE) 1998-10-21 EP claimed
CN-111398605-B Glycosylated hemoglobin measurement composition 龟甲万株式会社 2024-04-05 CN disclosed
WO-2024073718-A1 LOW DOSE IL-6 FORMULATIONS AND METHODS OF USE THEREOF Sonnet BioTherapeutics, Inc. (US) 2024-04-04 WO disclosed
WO-2023230620-A1 IL-12-ALBUMIN-BINDING DOMAIN FUSION PROTEIN FORMULATIONS AND METHODS OF USE THEREOF Sonnet BioTherapeutics, Inc. (US) 2023-11-30 WO disclosed
US-20210063346-A1 ELECTRO-BLOTTING DEVICES, SYSTEMS, AND KITS AND METHODS FOR THEIR USE Thermo Fisher Israel Ltd. (IL) 2021-03-04 US disclosed
WO-2020223565-A1 ANTI-IL-6 ANTIBODY FORMULATION CORVIDIA THERAPEUTICS, INC. (US) 2020-11-05 WO disclosed
EP-2598515-B1 TANDEM PURIFICATION OF PROTEINS PFIZER (US) 2016-09-21 EP disclosed
EP-2598515-A1 TANDEM PURIFICATION OF PROTEINS Pfizer Inc (US) 2013-06-05 EP disclosed
WO-2012014183-A1 TANDEM PURIFICATION OF PROTEINS PFIZER INC. (US) 2012-02-02 WO disclosed
US-20050019399-A1 Oral administering; mixture of amorphous drug and polymer; carvedilol EGALET LTD. (GB) 2005-01-27 US disclosed
US-20050006239-A1 Solution phase electrophoresis device, components, and methods Life Technologies Corporation 2005-01-13 US disclosed
US-20040182723-A1 Method for measuring by means of chemical sensor, and chemical sensor type measuring apparatus TANITA CORPORATION (JP) 2004-09-23 US disclosed
EP-1429734-A1 CONTROLLED RELEASE SOLID DISPERSIONS Egalet A/S (DK) 2004-06-23 EP disclosed
WO-2003024426-A1 CONTROLLED RELEASE SOLID DISPERSIONS EGALET A/S (DK) 2003-03-27 WO disclosed
EP-0876512-A1 METHODS FOR IDENTIFYING INHIBITORS OF RNA VIRUSES Viropharma Incorporated (US) 1998-11-11 EP disclosed
WO-1997027334-A1 METHODS FOR IDENTIFYING INHIBITORS OF RNA VIRUSES VIROPHARMA INCORPORATED (US) 1997-07-31 WO disclosed
EP-0646130-B1 SELECTIVE CROSSLINKING OF HEMOGLOBINS BY OXIDIZED, RING-OPENED SACCHARIDES HEMOSOL INC (CA) 1996-12-11 EP disclosed
US-5253198-A Three-dimensional optical memory SYRACUSE UNIVERSITY (US) 1993-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050006239-A1 Solution phase electrophoresis device, components, and methods PROC, RAB5IF, SPECC1L ALDH1A1 3301/4885USP2 2859/4885MAPT 3091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.